Yamasa began its long history of soy sauce brewing in 1645 in Chiba, Japan and now is one of the leading companies of soy sauce. “Quality first” is one of the policies Yamasa has inherited from its initiation and is also alive in Biochemicals Division. An enzyme called Nuclease P1 was discovered by our own research which selectively degrades RNA into 5'-nucleotides. In 1957 we invented an efficient separation technology of 5’-nucleotides and established an industrial manufacturing process of nucleic acid-based umami seasoning, inosine 5'-monophosphate and guanosine 5'-monophosphate. Since then, Yamasa has expanded its business specialized in nucleic acid related compounds which are now used in broad fields such as APIs, pharmaceutical intermediates, food additives, cosmetic ingredients and other industrial products. Along with our abundant experience and technology accumulated for many years, Yamasa provides products and contract services which realize your various needs.