Corning SAS

Avon Cedex, 
France
http://www.corning.com/reactors
  • Booth: 1043

Corning is one of the world’s leading innovators in materials science. For more than 160 years, Corning has applied its unparalleled expertise in specialty glass, ceramics, and optical physics to develop products that have created new industries and transformed people’s lives. Corning’s Advanced-Flow™ reactors (AFR) enable the continuous processing of chemicals with a smaller footprint than conventional batch reactors. They are also specially designed to enable the conversion of batch chemical processes to continuous processes. Corning’s AFR team provides customers with cost-effective solutions, specialized engineering support and process expertise. Compared with traditional batch reactors, Corning Advanced-Flow reactors can enable at least 100 times enhancement in mixing, 1,000 times improvement in heat transfer performance, and seamless and efficient scale-up from the lab to full-scale production of chemicals for the pharmaceutical, specialty and fine chemical industries.


 Press Releases

  • DELFT, THE NETHERLANDS – Corning, Zaiput Flow Technologies and Magritek recently presented an integrated continuous processing system at the 8th Symposium on Continuous Flow Reactor Technology for Industrial Applications organized by Teknoscience in November, 2016 using Corning’s G1 Silicon Carbide (SiC) reactor, the Zaiput Liquid-liquid phase separator and the Magritek benchtop 1H-NMR as a process analysis technology (PAT). Working together, these technologies offer a highly intensified and integrated system for continuous-flow chemical processing and also demonstrated the compatibility and flexibility of these systems.

    The Symposium aims to promote flow chemistry technology and provide the latest innovations and development from equipment providers for the fine chemistry and pharmaceutical industries. Within a short amount of time, the three companies created this experimental demonstration based on their collective knowledge of their individual systems and the ability to integrate them together.  “We wanted to showcase the possibilities of integration for continuous flow chemistry and thought this was the right venue to do this,” said Alessandra Vizza, regional commercial manager of Corning Reactor Technologies for Europe, Middle East, Africa, and North/South America. “Integration was really easy as each system could be directly connected to each other.”

    The chemical reaction demonstrated was a biphasic system with a phase transfer catalyst which integrated Corning’s G1 SiC reactor to allow for a high mixing capacity and chemical compatibility. The phase separator from Zaiput was installed at the outlet of the G1 reactor to separate the organic phase from the aqueous phase. A Spinsolve® from Magritek was then used on a stop flow mode to quickly analyze the chosen layer. Within ten seconds, the 1H-NMR spectrum could be obtained which allows for an accurate monitoring of the reaction processing.

    “Today, the goal is not only to realize continuous flow reaction, but also to have the possibility to perform the work-up and the analytics in continuous mode,” said Dr. Yi Jiang, global business director for Corning Reactor Technologies. “Working with Zaiput and Magritek allowed Corning to not only focus on its own proprietary flow reactor technology, but also to have the capacity and the ingenuity to work on a more global approach.”

    The demonstration was shown to more than 60 participants over the course of the three-day event and was the first time these three technologies were enabled in an integrated system with real chemistry.

    Contact AFR

    Europe, Middle East, Africa (EMEA),
    North and South America (NSA)

    Corning S.A.S.
    Reactor Technologies
    7 bis Avenue de Valvins
    CS 70156 Samois sur Seine
    77215 Avon Cedex, France
    t + 33 1 64 69 71 07
    f + 33 1 64 69 70 59
    reactors@corning.com

    “It was great being able to show how benchtop NMR can help in continuous processing systems to get immediate access to analytical data that can help to control the process,” Dr. Jürgen Kolz, Application and Support Manager of Magritek.

    Depending on customer needs, Corning will continue to working with Zaiput and Magritek on building combined systems that will allow continuous reaction, work-up, and more effective processes.

    “The symposium attendees were really impressed to see a fully integrated system that includes reaction, work-up and analytics all in very compact foot print,” said Dr. Andrea Adamo, the founder and CEO of Zaiput Flow Technologies. “The modularity of the components/technologies is a key aspect that enables the quick and easy development of integrated systems like this one which is where industry is headed.” 


 Products

  • Low-Flow Reactor
    Low-Flow reactor in borosilicate glass, suitable for performing lab scale process scouting and optimization, as well as for producing small quantities of material....

  • Low-Flow Reactor / Technical Specifications

    Flow rate: 2-10 ml/min
    Temperature range: -60°C to 200°C
    Maximum pressure: 18 barg

  • G1 Reactor
    Multi-purpose flow reactor, extremely flexible, the best scalable solution for process scouting and optimization from the R&D phase to the kilo-lab production. Highly resistant to corrosion : available in Borosilicate Glass and Silicon Carbide....

  • G1 Reactor / Technical Specifications

    Flow rate: 30-200 ml/min

    Temperature range: -60°C to 200°C

    Maximum pressure: 18 barg

  • G4 SIC Reactor
    Flow reactor for production in Silicon Carbide, with very small footprint and superior resistance to corrosion...

  • G4 SIC Reactor / Technical Specifications

    Processing capability > 300 kg/h

    Flow rate: 1000-8000 ml/min

    Temperature range: -60°C to 200°C

    Maximum pressure: 18 barg